Buffy Coats
Buffy Coats
Leukocyte Starting Materials
for your Therapy Development
Leukocyte Starting Materials
for your Therapy Development
The American Red Cross offers high-quality generic and specialty buffy coat products manufactured from healthy donor whole blood collections. These buffy coats are a good source of leukocytes for earlier stages of discovery and process development and can also be used in the manufacture of diagnostic products.

All buffy coats are 60 ML
Products are not diluted
Donor recallability for specialty buffy coats
Generic Buffy Coats
Generic buffy coats are manufactured from whole blood collected from a general blood donor. Corresponding donor demographic information on generic buffy coats is not available. Also, specific donor selection and donor recall ability for subsequent Leukopak product donations are not possible.
Generic buffy coats are shipped on the day of manufacture for next-day delivery. Units are packed and shipped per American Red Cross procedure, which allows for the client to select shipment at 1-6°C or 20-24°C.
Specialty Buffy Coats
Our specialty buffy coat products are collected from donors enrolled in our Specialized Donor Program, which allows clients to evaluate leukocytes from a broad selection of donors to inform future leukopak donor requests. Use of specialty buffy coat products from our Specialized Donor Program donors enables our clients to identify donor populations and select donor attributes that are more likely to be successful in their processes. Our clients can specify donor characteristic requirements—specific BMI range, ethnicity, HLA type, age, CMV status, and donor lifestyle and habits such as smoker vs. non-smoker.
To ensure raw material quality and consistency we utilize tools such as donor pre-screening, post-collection questionnaires, and testing to enable customized donor selection. Tests performed as part of the routine pre-screen process include a standard infectious disease panel and a complete blood count. Killer Cell Immunoglobulin-like Receptor (KIR) typing and additional specialized infectious disease testing may be performed on donors as requested to meet specific client requirements.
Utilization of American Red Cross specialty buffy coats as starting material for your therapy, enables you to have access to raw material collected and processed in a consistent manner as you scale from discovery through commercialization, helping to minimize variability in starting material.
Specialty buffy coats are shipped on the day of manufacture. Depending upon the client’s desired delivery geography, same-day delivery may be possible. Units will be packed and shipped per client instructions or standard American Red Cross procedure, based upon client preference.
You can also reach an account executive by calling 833-760-0625.
We look forward to speaking with you.