Clinical Indications

The presence of antibodies directed toward neutrophils results in their destruction and leads to a clinical condition known as neutropenia.  Neutropenia is defined as an abnormally low concentration of neutrophils.  Neutrophils are the most abundant white blood cells found in your blood stream and is essential in fighting off bacterial and fungal infections. Neutrophil antibodies can be found in the blood of women following pregnancy, multi-transfused individuals, patients with autoimmune disease and donors causing transfusion reactions.

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